Product Name
Human FcRn & B2M HEK293 Cell Line
Expression System
Mammalian Expression System
Concentration
Approximately 5 × 106 cells/vial
Application
This overexpression cell line is suitable for a wide range of applications, including but not limited to functional studies of the target gene/protein, receptor signaling and pathway analysis, ligand screening, and cellular localization studies. The fluorescent reporter enables real-time monitoring of expression and facilitates cell sorting and imaging-based assays. The cell line can also be used in drug discovery, target validation, and mechanism-of-action (MoA) studies.
Growth Conditions
DMEM + 10% FBS + 2 μg/mL Puromycin + 1% G418
Morphology
Epitheloid cell
Growth Properties
Adherent
Mycoplasma Status
Negative
Storage
90 % FBS + 10 % DMSO
Vapor phase of liquid nitrogen
Shipping Conditions
Dry Ice
Description
The human FcRn & B2M HEK293 cell line binds to rozanolixizumab, orilanolimab, and batoclimab with EC50 values of 0.4397 μg/mL, 0.3938 μg/mL, and 0.2899 μg/mL, respectively.
Industry Terms
Not Available to Industry
