Virus-like particles (VLPs) have been regarded as a convincing vaccine candidate. It looks similar to the real virus, but it does not carry infectious genomic material. However, they can still trigger a very effective immune response. Plants only need simple inorganic nutrients, water, carbon dioxide and sunlight to grow effectively. With the continuous improvement of the technology platform, Creative BioMart now opens VLP production services based on the plant transient expression system. What we provide is a safe, inexpensive and potentially unlimited way to produce therapeutic drugs quickly and flexibly.
At present, we have successfully produced many VLPs that are composed of one or more proteins with immunogenicity for clients.
pEAQ vectors are a series of plasmids designed for the simple and rapid production of recombinant proteins in plants. Their main feature is the use of cowpea mosaic virus super translation "CPMV-HT" expression system to provide high-yield recombinant protein through high translation efficiency without viral replication.
In general, the VLP will be produced through the following process:
| Step Description | Timeline |
| The vector which harbors the gene of interest is transferred into the E.coli for replication | 2-4 days |
| Transform the recombinant vector into A.tumefaciens | 2-3 days |
| Bacterial culture and aggro-infiltration | 2-3 days |
| VLP construction in plants | 5-9 days |
| VLP extraction and purification | —— |
In addition to the Plant Virus Vectors Delivery method, we also provide other three delivery strategies for clients to choose from. Please click the links below if you are interested.
With our professional research and development team and the latest protein expression and purification resources, we promise to deliver high-quality products for our customers. Customers who need our assistance are more than welcome to contact us or submit anonline inquiry. Our professional team will provide you with detailed guidance and solution ASAP.
Reference
